What is Hydroxyapatite Nanopowder/Nanoparticles?

Hydroxyapatite (HA) nanopowder consists of ultra-fine hydroxyapatite particles, a naturally occurring calcium phosphate compound that closely resembles human bone and teeth. Known for its excellent biocompatibility, osteoconductivity, and bioactivity, it is widely used in biomedical, dental, and orthopedic applications.

Chemical Properties and CAS Number

• Chemical Formula: Ca₁₀(PO₄)₆(OH)₂
• CAS Number: 1306-06-5
• Appearance: White fine powder
• Density: Approximately 3.16 g/cm³
• Melting Point: Decomposes above ~1,100°C
• Solubility: Slightly soluble in water, soluble in acids
• Chemical Stability: Highly stable under normal physiological conditions, resorbable in biological environments

Applications of Hydroxyapatite Nanoparticles

1. Biomedical and Orthopedic Applications

Used in bone grafts, implants, and orthopedic coatings to enhance bone regeneration and integration.

2. Dental and Oral Care

Applied in toothpaste, dental fillings, and coatings for dental implants to promote enamel remineralization and prevent tooth decay.

3. Drug Delivery and Biomedicine

Utilized as a carrier in targeted drug delivery, gene therapy, and regenerative medicine for controlled release of therapeutic agents.

4. Tissue Engineering and Regenerative Medicine

Employed in scaffolds and tissue engineering for bone and cartilage repair due to its osteoconductive properties.

5. Cosmetics and Skincare

Used in cosmetic formulations, including anti-aging creams and exfoliating products, due to its biocompatibility and remineralization effects.

6. Environmental and Water Treatment

Applied in wastewater treatment and heavy metal adsorption due to its high surface area and ion-exchange capabilities.

Pricing of Hydroxyapatite Nanopowder

Prices vary based on purity, particle size, synthesis method, and application-specific requirements:

• Industrial Grade: Typically ranges from $50 – $500 per kilogram
• High-Purity/Specialized Grade: Prices range from $1,000 – $5,000 per kilogram, used in biomedical, dental, and pharmaceutical applications.

Factors Influencing Hydroxyapatite Powder Prices

• Purity level and particle size distribution
• Industry-specific standards and certifications
• Processing complexity and synthesis method
• Bulk order volume and market demand

Conclusion

Hydroxyapatite (HA) nanopowder is a highly biocompatible material with diverse applications in biomedicine, dentistry, drug delivery, and tissue engineering. Its similarity to natural bone mineral, bioactivity, and osteoconductive properties make it a valuable material for medical and industrial applications. Pricing depends on purity, particle specifications, and industry demand.